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较大的鳞状细胞癌,其中部分肿瘤组织出现空洞,可能因为肿瘤的生长速度过快,超出了血液供应的能力。鳞状细胞癌是原发性肺癌的主要类型,主要发生于经常吸烟者。

This is a larger squamous cell carcinoma in which a portion of the tumor demonstrates central cavitation, probably because the tumor outgrew its blood supply.Squamous cell carcinomas are one of the more common primary malignancies of lung and are most often seen in smokers.

X线可见右肺上叶大鳞状细胞癌肿块。

This chest radiograph demonstrates a large squamous cell carcinoma of the right upper lobe.

肺鳞状细胞癌由肺门向胸膜扩散的又一例子。黑色区域表示被肿瘤包裹的炭尘色素。

This is another sqamous cell carcinoma that extends from hilum to pleura. The black areas represent anthracotic pigment trapped in the tumor.

胸部X线显示右肺下叶直径达5cm的鳞状细胞癌,其中直径1.5cm的高密度区是肿瘤发生后的钙化的肉芽肿。胸骨见到的钢丝圈是原来冠脉搭桥术时留下的。

This chest radiograph demonstrates a large 5 cm diameter squamous cell carcinoma of the right lower lobe. The 1.5 cm bright opacity in the middle of the mass is a calcified granuloma that was seen on lateral view to be behind the neoplasm. Additional calcified granulomatous areas are medial to the mass. The sternal wire loops are from a previous coronary artery bypass procedure.

鳞状细胞癌,癌组织有由多边形细胞组成的癌巢,多边形细胞边界清楚,胞质为粉红色。细胞核染色深,形状有角。

This is the microscopic appearance of squamous cell carcinoma with nests of polygonal cells with pink cytoplasm and distinct cell borders. The nuclei are hyperchromatic and angular.

高倍镜下,细胞边界清楚、细胞间桥、粉红色胞质均是鳞状细胞癌的特征。这些特征在高分化肿瘤中均可见(肿瘤细胞更接近来源组织的细胞)。

The pink cytoplasm with distinct cell borders and intercellular bridges characteristic for a squamous cell carcinoma are seen here at high magnification. Such features are seen in well-differentiated tumors (those that more closely mimic the cell of origin).

鳞状细胞癌,左上有一癌巢,有角化珠,呈漩涡状。右边分化较差,并且可见几个深染的病理性核分裂象。

In this squamous cell carcinoma at the upper left is a squamous eddy with a keratin pearl. At the right, the tumor is less differentiated and several dark mitotic figures are seen.

周围型肺腺癌。腺癌和大细胞未分化癌更常发生在肺边缘。腺癌是单细胞类型的原发肺癌,多发生于非吸烟者和已戒烟者。如果肿瘤局限于肺(早期),切除后痊愈的机会更大。单个肿块往往说明是原发瘤,而不是转移瘤。

This is a peripheral adenocarcinoma of the lung. Adenocarcinomas and large cell anaplastic carcinomas tend to occur more peripherally in lung. Adenocarcinoma is the one cell type of primary lung tumor that occurs more often in non-smokers and in smokers who have quit. If this neoplasm were confined to the lung (a lower stage), then resection would have a greater chance for cure. The solitary appearance of this neoplasm suggests that the tumor is primary rather than metastatic.

细支气管肺泡癌是肺腺癌的另一类型。呈多病灶多样性的肺实变外观。右肺上叶大部分区域呈现灰白色外观。

This is another type of adenocarcinoma of lung known as bronchioloalveolar carcinoma. Seen here is the multifocal variant that appears grossly (and on chest radiograph) as a pneumonic consolidation. Most of the upper lobe toward the right has a pale tan to grey appearance.

镜下,细支气管肺泡癌由柱状细胞构成,柱状上皮细胞沿肺泡壁增生。细胞分化良好。总的来说,比大多数其它原发性肺癌预后要好。

Microscopically, the bronchioloalveolar carcinoma is composed of columnar cells that proliferate along the framework of alveolar septae. The cells are well-differentiated. These neoplasms in general have a better prognosis than most other primary lung cancers.


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