SLE时新月体性肾小球肾炎:脏层上皮细胞增生形成新月体
肾小球内由增生的壁层上皮细胞组成的新月体。因为展迅速,新月体性肾小球肾炎也称作快速进行性肾小球肾炎。它有多种病因,本例是由SLE引起。左下角的肾小球毛细血管管壁显著增厚(狼疮性肾炎时的“线圈”征)。
Seen here within the glomeruli are crescents composed of proliferating epithelial cells. Crescentic glomerulonephritis is known as rapidly progressive glomerulonephritis (RPGN) because this disease is very progressive. There are several causes, and in this case is due to SLE. Note in the lower left glomerulus that the capillary loops are markedly thickened (the so-called "wire loop" lesion of lupus nephritis).