链球菌感染后的细胞大量增生,表现为在毛细血管袢内及周围的血管内皮细胞、系膜细胞增生,伴中性粒细胞和巨噬细胞浸润。可在A组β溶血性链球菌感染数周后发生。病人抗O(ASO)滴度明显升高。
The hypercellularity of post-streptococcal glomerulonephritis is due to increased numbers of epithelial, endothelial, and mesangial cells as well as neutrophils in and around the capillary loops. This disease may follow several weeks after infection with certain strains of group A beta hemolytic streptococci. Patients typically have an elevated anti-streptolysin O (ASO) titer.