乙二醇中毒引起肾小管扩张和空泡状改变。急性肾小管坏死有很多原因，乙二醇中毒是其中的一种。由毒素引起的肾小管坏死通常弥散性累及肾小管，而由缺血（如心衰引起的严重低血压）引起的肾小管坏死则成片状受累。
The tubular vacuolization and dilation here is a result of ethylene glycol poisoning. This is representative of acute tubular necrosis (ATN), which has many causes. ATN resulting from toxins usually has diffuse tubular involvement, whereas ATN resulting from ischemia (as in profound hypotension from cardiac failure) has patchy tubular involvement.
