乳腺浸润性导管癌浸润乳腺周围组织。因为大量胶原纤维的形成，使中央白色区域非常坚硬并有硬粒感，称之为硬癌。由于营养不良性钙化导致硬粒感的出现。
This infiltrating ductal carcinoma of the breast is definitely infiltrating the surrounding breast. The central white area is very hard and gritty, because the neoplasm is producing a desmoplastic reaction with lots of collagen. This is often called a "scirrhous" appearance. There is also focal dystrophic calcification leading to the gritty areas.