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弥漫性肺泡损伤早期透明膜隔开肺泡


弥漫性肺泡损伤(DAD)的肺,DAD是许多严重肺损伤的最后结局。DAD的早期,有透明膜隔开肺泡,如图所见。
后来,就可看到II型肺泡上皮细胞增生,接着是间质出现炎症并纤维化。需高压氧来治疗DAD引起的低氧血症。病因继续作用将进一步加重疾病。
This is the microscopic appearance of diffuse alveolar damage (DAD) in the lung. DAD is simply the final common pathway for a variety of severe lung injuries. In early DAD, there are hyaline membranes, as seen here, lining alveoli. Later, type II pneumonocyte proliferation and then interstitial inflammation and fibrosis are seen. High oxygen tensions needed to treat the hypoxia resulting from DAD and its etiologies further potentiates this disease.

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