图示肺矽结节。它主要由成束相互交织的粉红色胶原纤维组成。此处炎症反应轻。暴露于二氧化硅的强度越大,暴露时间越长,决定了矽肺结节的数目及肺疾病的发展。矽肺使肺癌的风险增加了2倍。
A silicotic nodule in lung is seen here. It is composed mainly of bundles of interlacing pink collagen. There is a minimal inflammatory reaction. The greater the degree of exposure to silica and increasing length of exposure determine the amount of silicotic nodule formation and the degree of restrictive lung disease. Silicosis increases the risk for lung carcinoma about 2-fold.