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支气管哮喘大量嗜酸性粒细胞


高倍镜下支气管哮喘可见大量嗜酸性粒细胞,可见明显的粉红色嗜酸性颗粒。哮喘有2种临床类型,它们彼此相关。
外源性哮喘:它与Ⅰ型超敏反应(变态反应)有明显联系,哮喘突然发作与吸入变应原有关。最常在童年发生。
内源性哮喘:哮喘发作与呼吸道感染有关,暴露于严寒,锻练,压力,吸入刺激物,药(如阿斯皮林)。成年人最常受其影响。

At high magnification, the numerous eosinophils are prominent from their bright red cytoplasmic granules in this case of bronchial asthma. There are two major clinical forms of asthma that can overlap.

  • Extrinsic asthma: there is typically an association with atopy (allergies) mediated by type 1 hypersensitivity, and asthmatic attacks are precipitated by contact with inhaled allergens. This form occurs most often in childhood.

  • Intrinsic asthma: asthmatic attacks are precipitated by respiratory infections, exposure to cold, exercise, stress, inhaled irritants, and drugs such as aspirin. Adults are most often affected.


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