高倍镜下，肉芽肿内可见上皮样细胞，胞核染色较浅、胞质粉红色。此种细胞融合成团，称巨细胞。感染性肉芽肿形成典型的巨细胞叫朗格罕斯巨细胞，它的细胞核沿细胞边缘排列。肉芽肿性炎持续数月到数年。
At high magnification, the granuloma demonstrates that the epithelioid macrophages are elongated with long, pale nuclei and pink cytoplasm. The macrophages organize into committees called giant cells. The typical giant cell for infectious granulomas is called a Langhans giant cell and has the nuclei lined up along one edge of the cell. The process of granulomatous inflammation takes place over months to years (did you ever hear of a committee action that was completed in a short time?)
