边界清楚的肉芽肿，圆形。图片中心的一个肉芽肿包含几个朗格罕斯巨细胞。肉芽肿由巨噬细胞而来的上皮样细胞,以及少量淋巴细胞，中性粒细胞，浆细胞，成纤维细胞组成。局部化的较小的肉芽肿提示免疫反应相当强。
Well-defined granulomas are seen here. They have rounded outlines. The one toward the center of the photograph contains several Langhans giant cells. Granulomas are composed of transformed macrophages called epithelioid cells along with lymphocytes, occasional PMN's, plasma cells, and fibroblasts. The localized, small appearance of these granulomas suggests that the immune response is fairly good.
