当存在广泛的干酪性坏死并且肉芽肿累及较大的支气管时，大量的坏死物排出，留下空洞。对于伴有大肉芽肿的肺结核而言，空洞非常典型，常发生于肺上叶。
When there is extensive caseation and the granulomas involve a larger bronchus, it is possible for much of the soft, necrotic center to drain out and leave behind a cavity. Cavitation is typical for large granulomas with tuberculosis. Cavitation is more common in the upper lobes.
