伴有毛细血管扩张的肺充血和血液流入肺泡腔,共同引起内部充满含铁血黄素的巨噬细胞增多,如图所示,红细胞破裂形成的棕色含铁血黄素颗粒出现在巨噬细胞的胞质内。由于与充血性心力衰竭有关,因此也称为心力衰竭细胞。
Pulmonary congestion with dilated capillaries and leakage of blood into alveolar spaces leads to an increase in hemosiderin-laden macrophages, as seen here. Brown granules of hemosiderin from break down of RBC's appear in the macrophage cytoplasm. These macrophages are sometimes called "heart failure cells" because of their association with pulmonary congestion with congestive heart failure.