图示:淋巴瘤bcl-2阳性
此种基因的过度表达抑制了细胞凋亡,淋巴细胞数量增多。
免疫过氧化物酶染色显示集中在淋巴滤泡内和淋巴滤泡之间。
This is an example of bcl-2 positivity in a lymphoma. In this case, the overexpression of this oncogene results in an inhibition of apoptosis, and increased numbers of lymphocytes. The immunoperoxidase stain here highlights the lymphocytes in lymphoid follicles and interfollicular areas.