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免疫过氧化物酶染色:乳腺癌c-erb-B2呈阳性

免疫过氧化物酶染色:乳腺癌c-erb-B2呈阳性

图示:乳腺癌c-erb-B2呈阳性

此癌基因通过使正常原癌基因数百次的复制产生一种能驱使细胞非调节性生长的蛋白。
免疫过氧化物酶染色显示在细胞周围可见褐色的膜状物。

Here is an example of c-erb-B2 positivity in a breast carcinoma. This oncogene acts via reduplication of the normal proto-oncogene hundreds of times, leading to production of a protein product that drives unregulated cell growth. This is detected here by immunoperoxidase staining with the brown reaction product concentrated in a perimembranous pattern around the cells.


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