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电镜:淀粉样物质由原纤维的β-折叠组成

电镜,淀粉样物质是由原纤维的β-折叠组成。可见不规则的灰色物质。当淀粉样蛋白由免疫球蛋白轻链组成时,那么它就是“免疫细胞衍生性淀粉样变性”,当它来自于血清淀粉相关蛋白时,就是“反应性系统性淀粉样变性”。根据对器官的影响,“淀粉样物质就是细胞外蛋白样物质”。


By electron microscopy, amyloid is composed of a "beta-pleated sheet" of fibrils, seen here as irregular grey material. When the amyloid protein is made up of immunoglobulin light chains, then it is "AL amyloid" and when it is derived from serum amyloid-associated protein, then it is "AA amyloid." In terms of the effect upon the organs, "amyloid is amyloid".

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