高倍镜下,慢性血管排斥反应引起肾动脉显著增厚和纤维化。出现间质纤维化和慢性炎症,慢性排斥反应通常在移植后数月到数年缓慢发生,不象急性排斥反应且难于治疗。
At high magnification, the renal arteries with chronic vascular rejection are markedly thickened and fibrotic. There is interstitial fibrosis and chronic inflammation. Such chronic rejection usually occurs slowly over several months to years following transplantation. This disease, unlike acute rejection, is difficult to treat.