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青霉素过敏:急性喉头水肿

青霉素过敏时出现急性喉头水肿而致死。
为I型超敏反应,肥大细胞上的IgE抗体与抗原反应,肥大细胞快速释放组胺和其它介质致水肿发生。


The acute laryngeal edema seen here that killed the patient was due to an anaphylactic reaction to penicillin. Such an allergy is a form of type I hypersensitivity reaction in which there is preformed IgE antibody on mast cells that quickly reacts with an antigen. The mast cells release histamine and other mediators that lead to the edema.

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