自身免疫性疾病筛查常用抗核抗体(ANA)检测,血清与组织的底物温育,抗核抗体和相应的核抗原结合， 接着加入荧光抗体,在荧光显微镜下观察,看是否被染色。图示典型的抗核抗体染色阳性，呈均质型。
Screening for autoimmune diseases is often performed with the antinuclear antibody (ANA) test in which patient serum is incubated with a tissue substrate to which any autoantibodies to nuclear antigens will bind. Then, a fluorosceinated antibody is added and the tissue is observed under fluorescence microscopy to see if staining is present. Seen here is the typical "homogenous" pattern(均质型) of nuclear staining of a positive ANA.
