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胆道闭锁:新生儿巨细胞肝炎


此图为胆道闭锁的主要不同诊断:这是一例新生儿巨细胞肝炎。图中可见具有病灶肝细胞坏死、巨细胞转化、淋巴细胞浸润、枯否细胞增生和胆汁淤积(此图未显示)的肝小叶紊乱。新生儿肝炎可为先天性或由病毒感染引起。许多新生儿在几个月内康复。
Seen here is the major differential diagnosis of biliary atresia: this is neonatal giant cell hepatitis. There is lobular disarray with focal hepatocyte necrosis, giant cell transformation, lymphocytic infiltration, Kupffer cell hyperplasia, and cholestasis (not seen here). Neonatal hepatitis may be idiopathic or of viral origin. Many neonates recover in a couple of months.

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