显性遗传性多囊肾（DPKD）患者的肝脏中具有大量包囊。本病发病于成年，并在中年时发生肾衰。多囊改变有时也可影响肝脏（如图所示）。胰腺很少受累。DPKD患者还可发生脑动脉的小动脉瘤。
Numerous cysts appear in this liver from a patient with dominant polycystic kidney disease (DPKD). Such cases occur in adults and manifest with renal failure beginning in middle age. Sometimes the liver (as seen here) can be affected as well by polycystic change. Less commonly the pancreas is involved. These patients with DPKD can also have berry aneurysms in the cerebral arteries.
