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药物性肝损伤:肝细胞广泛坏死


药物对乙酰氨基酚(退热净)使用过量患者表现为广泛的肝细胞坏死。右侧的肝细胞已经死亡,左侧的濒临死亡。这种表现可见于多种肝脏中毒时。急性肝功能衰竭可导致肝性脑病。
There is extensive hepatocyte necrosis seen here in a case of acetaminophen overdose. The hepatocytes at the right are dead, and those at the left are dying. This pattern can be seen with a variety of hepatotoxins. Acute liver failure leads to hepatic encephalopathy.

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