如果淤血显著，由于肝小叶3区(位于中央静脉周围)血液含氧量不足，将发生肝小叶中心坏死。图中中央静脉周围坏死肝细胞中的浅褐色色素为脂褐素。
If the passive congestion is pronounced, then there can be centrilobular necrosis, because the oxygenation in zone 3 of the hepatic lobule is not great. The light brown pigment seen here in the necrotic hepatocytes around the central vein is lipochrome.
