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病毒性肝炎:点状坏死


病毒性肝炎时少数肝细胞发生坏死称为点状坏死。甲肝很少引起显著的坏死,但乙肝能够导致广泛肝细胞坏死的爆发型肝炎。右侧箭头下方,大的粉红色细胞正在发生“气球样变”。进一步发展,如左侧箭头所示,濒临死亡的肝细胞正浓缩形成嗜酸性小体。
Individual hepatocytes are affected by viral hepatitis. Viral hepatitis A rarely leads to signficant necrosis, but hepatitis B can result in a fulminant hepatitis with extensive necrosis. A large pink cell undergoing "ballooning degeneration" is seen below the right arrow. At a later stage, a dying hepatocyte is seen shrinking down to form an eosinophilic "councilman body" below the arrow on the left.

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