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骨髓增生脾肿大


明显增大的脾(标尺显示有15厘米长)。这样的脾肿大通常预示有骨髓增生型疾病,例如慢性髓性白血病或骨髓纤维化。包膜下可见黄褐色梗死灶。淤血性脾肿大(肝硬化门脉高压的表现)不可能800克。脾大于1000克暗示有骨髓增生、淋巴组织增生或造血系统病变。
This is a markedly enlarged spleen (the ruler is 15 cm long). Such massive splenomegaly is usually indicative of some myeloproliferative disease such as chronic myelogenous leukemia or myelofibrosis. There are subcapsular yellow-tan infarcts. Congestive splenomegaly (as with portal hypertension in cirrhosis of the liver) is unlikely to increase the size of the spleen over 800 gm. A spleen >1000 gm suggests a myeloproliferative, lymphoproliferative, or hematopoietic disorder.

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