脾肿大常见原因之一是肝硬化门静脉高压。在美国，慢性酒精中毒引起的小结节型肝硬化比乙型或丙型肝炎引起的小结节型肝硬化更常见。图示脾的紫色表面上也显示有不规则的苍白色纤维性斑片，称为玻璃样脾周围炎。
One of the most common causes for splenomegaly is portal hypertension with cirrhosis of the liver. Micronodular cirrhosis from chronic alcoholism is more common in the U.S. than macronodular cirrhosis following hepatitis B or C infection. Note that this spleen also shows irregular tan-white fibrous plaques over the purple surface. This "sugar icing" has the name hyaline perisplenitis.
