中倍镜下结节硬化型霍奇金淋巴瘤有明显的纤维束。霍奇金淋巴瘤的分期对治疗和预后都很重要 。分期常常是通过放射手段完成的，CT扫描用来定位病变淋巴结，超声和胸片用来判断淋巴结的大小和肝、脾病变。对受累淋巴结进行活检是非常重要的，骨髓活检也是如此。因X线的广泛应用，剖腹探察现在已很少用。
At medium power, nodular sclerosing Hodgkin's disease has prominent bands of fibrosis. Staging of Hodgkin's disease is important to try and determine therapy and the prognosis. Staging is often done by radiographic means, with CT scans used to determine where lymphadenopathy is located, ultrasonography to determine size and lesions of liver and spleen, and chest radiograph. Histologic diagnosis is typically made from biopsy of an involved lymph node. A bone marrow biopsy is typically performed as well. Staging laparotomy is less commonly used nowadays because the radiographic procedures are excellent.
