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移植后淋巴组织增生症(PTLD)


器官移植尤其是心脏移植(当然也包括少量肾移植和骨髓移植)后,免疫抑制剂治疗可促进EB病毒感染T细胞。图示免疫过氧化物酶染色可见EB病毒,是移植后淋巴组织增生症(PTLD),它象淋巴瘤,但免疫抑制减弱时可消退。
Following organ transplantation, particularly for heart, but also to a lesser extent with kidney and bone marrow, immunosuppressive therapy may promote an expansion of Epstein-Barr virus (EBV) infected T-cells, seen here with immunoperoxidase staining for EBV. This is a post-transplantation lymphoproliferative disorder (PTLD), which acts like a lymphoma, but will recede when immunosuppression is diminished, if possible.

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