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Pelger-Huet异常


如果大部分嗜中性粒细胞出现二叶,提示一种罕见的、遗传的、被称为Pelger-Huet异常。这是杂合子的情况。纯合子是致命的。诊断时,如果你得到的主要是经手工鉴别计数的结果,那么WBC计数却是正常的,或者患者显示无感染或炎症。
If most of the neutrophils appear bilobed, this is indicative of an uncommon condition known as Pelger-Huet anomaly, an inherited condition. This is the heterozygous form. The homozygous form is fatal. Just be aware of this condition when you get back a manual differential count with mostly bands, but the WBC count is normal or the patient shows no signs of infection or inflammation.

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