巨幼细胞贫血(大细胞性贫血)中多叶核嗜中性粒细胞，有8叶，而不是正常的3到4叶。
这种贫血与叶酸或维生素B12缺乏有关。另外， RBC的体积也增加了（大红细胞症，在血涂片中很难鉴别)。
Here is a hypersegmented neutrophil that is present with megaloblastic anemias. There are 8 lobes instead of the usual 3 or 4. Such anemias can be due to folate or to B12 deficiency. The size of the RBC's is also increased (macrocytosis, which is hard to appreciate in a blood smear).
