疱疹性溃疡有明显的界限。左边溃疡基底面缺少鳞状上皮仅存有坏死的碎片。病变活检显示，鳞状上皮细胞核内包涵体提示为单纯疱疹病毒性食管炎。该病人由于化疗产生了免疫抑制。
A herpetic ulcer is seen microscopically to have a sharp margin. The ulcer base at the left shows loss of overlying squamous epithelium with only necrotic debris remaining. Biopsies of these lesions reveals intranuclear inclusions in squamous epithelial cells indicative of herpes simplex virus esophagitis. This patient was immune compromised from chemotherapy.
