在白质上看到的是脱髓鞘的大“斑块”，斑块呈灰褐色外观，是多发性硬化症( MS ) 的典型表现。这些斑块导致神经系统功能短暂或逐步丧失的临床症状。因为这种疾病是多病灶的，并且损害随时间改变加重的，所以临床表现也是多种多样。
Seen here in white matter is a large "plaque" of demyelination. The plaque has a grey-tan appearance. Such plaques are typical for multiple sclerosis (MS). These plaques lead to the clinical appearance of transient or progressive loss of neurological function. Since the disease is multifocal and the lesions appear over time, the clinical findings can be quite varied.