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肝细胞脂褐素沉着

肝细胞脂褐素沉着

图示:肝细胞脂褐素沉着

肝细胞中可见黄褐色颗粒,脂褐素沉着随着年令的增长而加重,是细胞自噬溶酶体内未被消化的细胞器碎片残体。多发生于肝脏和心脏。

The yellow-brown granular pigment seen in the hepatocytes here is lipochrome (lipofuscin) which accumulates over time in cells (particularly liver and heart) as a result of "wear and tear" with aging. It is of no major consequence, but illustrates the end result of the process of autophagocytosis in which intracellular debris is sequestered and turned into these residual bodies of lipochrome.


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