过碘酸希夫染色显示了乳腺Paget病Paget氏细胞里的黏蛋白。此为他们起源于下方的导管癌的证据。通过免疫过氧化物酶染色可知他们也是角蛋白阳性与上皮膜抗原阳性。 A PAS stain demonstrates mucin within the Paget's cells of Paget's disease of the breast. This is evidence for their origin from an underlying ductal carcinoma. By immunoperoxidase staining, they will also be keratin positive and epithelial membrane antigen positive.