如图，在有粉刺癌的导管中心区细胞常为坏死性与钙化的。中央坏死导致肉眼下特征性干酪样物质受压从导管内溢出（呈粉刺样）。 The cells in the center of the ducts with comedocarcinoma are often necrotic and calcify, as shown here. This central necrosis leads to the gross characteristic of extrusion of cheesy material from the ducts with pressure (comedone-like).