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Paget骨病破骨-成骨期(偏振光显微镜)

Paget病病人混合破骨-成骨期的骨。一行成骨细胞正在中右部形成新骨,而腔隙内的多核破骨细胞正在中左与中底部破坏骨。结果形成了不均一的板层结构的骨的不协调嵌合体。此期的前一期为溶解期,紧接着为硬化期。

另例Paget骨病

This is Paget's disease of bone in which the mixed osteoclastic-osteoblastic stage is present. A line of osteoblasts is present a the center-right forming new bone, but lacunae containing multinucleate osteoclasts are at the center left and lower center destroying bone. The result is a patchwork mosaic of bone without an even lamellar structure. This stage is preceded by a mainly lytic phase and is followed by a "burnt out" sclerotic phase.


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